Microparticle Synthesis

DESCRIPTION

Solid, spherical microparticles are:

• Made with PEG 

• Can be functionalized with various peptides, affinity agents, etc. 

• Compatible with most cells types and flow cytometers. 

APPLICATIONS

You can use solid particles at a micrometer scale for a wide variety of applications. 

1. Diagnostics: 

Perform cheap, easy high-throughput immunoassays. 

Advantages: Able to perform high-quality, high-throughput diagnostic assays without the need for large pieces of equipment and/or skilled expertise. Only requires these particles, oil, and standard flow cytometers

Options: These particles can contain functional groups (e.g. biotin) such that capture groups and amplification agents can be attached. 

Method: By agitating the particles with oil and solution containing your desired target, you can form droplets instrument-free and amplify signals to perform immunoassays at a digital level. The particles can then be run through FACS for screening. 

2. Tissue Engineering: 

Anneal particles together to form a scaffold for tissue engineering applications. 

Advantages: The uniform pores in between particles provide space for cells to grow and for the diffusion of gas/nutrients, providing better cell growth characteristics than other tissue scaffolds. 

Note: Please contact us with your exact needs as further variations may be available. 

PUBLICATIONS

https://www.nature.com/articles/nmat4294

https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201903147

https://pubmed.ncbi.nlm.nih.gov/33168979/

KEY TERMS

Materials, Screening, Diagnostics, Immunoassays, Tissues engineering