Microparticle Synthesis

DESCRIPTION

Particles contain a hollow inner component made with a hydrophilic material (PEG) and a hydrophobic outer layer (made with PPG). Droplets are formed in the hollow inner component. The material around the hollow cavity can be functionalized with biotin such that desired reagents for immunoassays can be added. Particles come in various sizes for shape-based barcoding.

APPLICATONS

Diagnostic Assay

Advantage: 

Concentric, multimaterial particles give you an easy, instrument-free way to form droplets for diagnostic assays.

Method:

• Agitating the particles with oil and water

• Form droplets that can compartmentalize your desired targets to eliminate cross-talk.

• The interior component of the particles can also be functionalized to enzymatically amplify signals.

• The system yields a detection limit of <1pM with a dynamic rage of at least 3 orders of magnitude.

• Enables you to multiplex by purchasing particles of different shapes. 

Please inquire for additional options available.

PUBLICATIONS

        https://pubs.rsc.org/en/content/articlelanding/2020/LC/D0LC00698J#!divAbstract                

KEY TERMS

 Diagnostics, Immunoassays, Screening